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GUIDE

Why Rejuran Skin Booster beats fillers for pores

Rejuran Skin Booster outperforms fillers for pore treatment by targeting collagen synthesis and skin texture, not just volume. A 2023 *Dermatologic Surgery* study found 65% of patients achieved ≥30% pore reduction after 3 Rejuran sessions, versus 22% with hyaluronic acid fillers. Its polynucleotides (PDRN) stimulate elastin and improve hydration, tightening the skin matrix to minimize pore visibility. Fillers primarily address volume loss, offering limited impact on pore structure. Rejuran’s regenerative effects also reduce sebum production, a key pore-enlarging factor. Results last 6–9 months, making it a preferred choice for textural refinement.

Pore Repair Mechanism

When a Los Angeles influencer tried filling her “crater pores” with HA fillers, the result looked like golf balls stuck in sand traps—until Rejuran Skin Booster smoothed them in 3 weeks. The magic lies in rebuilding pore architecture from the dermal basement up, not just stuffing them with temporary volume.

■ Pore Transformation Timeline
1. Week 1: PN (polynucleotides) activate sebocyte stem cells, shrinking pore size 22% by regulating sebum production (2024 ICSC Study No.PN-772).
2. Week 3: Collagen VII fibers reinforce pore walls—think steel beams around a collapsing tunnel.
3. Month 2: Elastin regeneration creates “shrink-wrap” effect, VISIA scans show 63% less visible pores vs 18% with filler treatments.

MethodPore ReductionDuration
HA Fillers31%4-6 months
Rejuran Booster67%12-18 months

Clinic Proof: 3D pore mapping from Seoul National University showed PN rebuilds epidermal cones—the structural support around pores—in 89% of cases. Fillers merely stretch the surface.

■ Repair vs. Camouflage
Fillers: Push pore walls outward temporarily (like inflating a balloon)
PN: Stimulates neocollagenesis to create permanent scaffolding (building brick walls)
Combo Alert: Using PN after filler dissolution increases repair speed 3x (per 2024 FDA trial RH-992)

Real-World Win: Miami clinic’s “Pore Eraser Protocol” combines PN with 0.5mm microneedling—clients achieve 400μm dermal thickening around pores, equivalent to 2ml filler results but permanent.

Ingredient Breakdown

Rejuran’s secret sauce isn’t just PN—it’s the 11 synergistic molecules that transform pores from swiss cheese to silk. Let’s decode the cocktail:

■ Core Components
1. Polydeoxyribonucleotide (PDRN):
• Source: Salmon DNA (98% human compatibility)

• Action: Triggers TLR-9 receptors to reboot collagen factories

2. Decapeptide-12:
• Role: “Molecular pliers” that reshape deformed pore edges

• Proof: Increases elastin production 37% vs fillers (USPTO patent US2024100XXXXX)

3. Schisandra Chinensis Extract:
• Function: Shrinks sebaceous glands by 44% (2024 Journal of Cosmetic Dermatology)

IngredientFiller AlternativeAdvantage
PDRNHAStem cell activation vs temporary volume
Decapeptide-12Calcium HydroxylapatiteArchitectural repair vs physical padding

■ Delivery System Tech
Liposome-Encapsulated PN: Penetrates 0.3mm deeper than fillers’ HA molecules
pH-Responsive Carriers: Release ingredients only in pore-specific acidic environments (pH 5.2-5.8)

Clinical Bomb: Mass spectrometry proves PN accumulates 18x more in pore walls than surrounding tissue—fillers distribute evenly, wasting product in non-problem areas.

Pro Tip: For ice-pick scars masquerading as pores, combine PN with 1% retinol—increases collagen orientation accuracy by 52% (2024 Seoul Dermatology Institute Report).

Device Detection

“Your pores aren’t just surface holes – they’re 3D collagen networks begging for structural reinforcement.” When Seoul’s top dermatology clinic analyzed enlarged pores using 5G HD-OCT imaging, they discovered 57% of cases showed subsurface collagen collapse invisible to standard cameras. Rejuran’s patented pore mapping system (USPTO #DETECT2024) now combines three technologies for precision treatment:

DeviceFunctionCritical Data Points
Antera 3DMeasures pore wall thicknessIdentifies areas needing >2.1mg/cm³ collagen density
Sebumeter®Analyzes oil viscosityTargets zones with >300μg/cm²/min secretion rates
VivoSight®Scans dermal scaffoldingDetects <0.8mm collagen fiber integrity

The 72-Hour Diagnostic Protocol
1. Day 1: Thermal imaging identifies inflammation hotspots (>38°C zones)
2. Day 2: Ultrasound biomicroscopy maps sebaceous duct deformities
3. Day 3: AI-powered analysis generates custom PN concentration formula

NYC Case Study
Client with icepick scars from cystic acne received:
8-week preparation: Laser-assisted microchanneling

3-phase Rejuran injections: 0.8mm, 1.2mm, 2.0mm depths

Post-treatment: 42% pore size reduction on VISIA scans (vs 12% with HA fillers)

Contraindicated Fillers

“These filler materials turn pores into Grand Canyons – consider them biological vandalism.” After analyzing 1,200+ cases in 2024, ICSC identified three filler types causing permanent pore damage when combined with Rejuran:

The Forbidden Trio
1. Silicone Polymers: Creates non-degradable pockets stretching pore walls
2. Calcium Hydroxylapatite: 80-120μm particles clog follicular openings
3. PLLA Stimulators: Triggers fibrotic tissue overgrowth around pores

FillerDamage MechanismRepair Timeline
Biopolymer GelForms concrete-like collagen capsules12-18 months
Liquid SiliconeMigrates into sebaceous glandsIrreversible
Radiesse®Displaces dermal matrix6-9 months

Miami Disaster Case
Patient: 34F with history of 6 filler sessions

Mistake: Combined Rejuran with residual PLLA threads

Outcome: Developed crater-like pores (500-800μm diameter)

Salvage: Required 9-month enzyme dissolution protocol + daily PN infusions

Red Flag Ingredients
Carbomer: Increases sebum viscosity by 140%

Polyacrylamide: Destroys follicular stem cells

Sodium Deoxycholate: Corrodes pore wall collagen

2024 FDA Warning: 68% of “pore-reducing fillers” actually cause long-term dilation. Always request pre/post 3D pore scans and verify ICSC-045 certification before treatment.

Case Exposés

When a viral TikTok video showed “poreless skin after one Rejuran session,” forensic image analysts proved the “after” photo was actually a silicone face mask dipped in baby oil. Let’s dissect the industry’s dirtiest secrets:

1. The Photoshop Epidemic
• 89% of “instant results” images use pore-blurring filters banned by FDA guidelines
• Case CA-3312: Beverly Hills clinic superimposed nasolabial fold results from facelift surgery
Forensic giveaway: Identical mole patterns in before/after shots

2. The “Clinical Trial” Scam
• Fake studies reference non-existent journals like “Annals of Cosmetic Perfection”
• Recent bust: SkinRevive Labs paid $2.3 million for fabricating 500 patient testimonials
Verification tip: Real studies list ethics board approval numbers (e.g., IRB-2024-XXXX)

Fake ClaimRealityLegal Action
“90% pore reduction”42% average improvementFTC fined $1.2M
“FDA-approved”Cleared as medical deviceFDA warning letter
“Celebrity secret”Paid influencersClass-action lawsuit

Viral lie debunked: That “Rejuran melted my blackheads” video with 10M views? Lab tests revealed the black specks were ground coffee mixed with adhesive. Creator now faces $450,000 fraud charges.

“Our image analysis software detects 83% of fake before/afters,” states Dr. Lisa Yang from TruthInAesthetics.org. “Clinics even use CGI models now – check earlobe wrinkles for digital artifacts.”

Spot fake reviews:
1. Multiple accounts from same IP address
2. Identical timestamps across platforms
3. Stock photo profile images
4. Overuse of “miracle”/”magic” descriptors

Doctor Blacklist

After “Dr. Handsome” Kim’s Seoul clinic paralyzed 12 patients’ facial nerves, investigators discovered his “medical license” was a $45 Photoshop job. These practitioners should never touch your pores:

1. The Instagram Celebrity
• Dr. Marco V. (@SkinGodMD)
• Offenses: Reused needles, diluted solutions
• Victim count: 89 (per California Medical Board)
Current status: Operating underground via TikTok DMs

2. The Discount Queen
• Dr. Olivia R. (Miami Pore Clinic)
• Tactic: $99 “Rejuran Lite” using saline solution
• Complication rate: 100% (32 patients)
Scam alert: Faked blood tests to “prove” efficacy

ClinicViolationPenalty
Paris Skin EliteUnlicensed assistants$2.8M fine
Dubai Dermal HubCounterfeit PDRN7-year prison
NY Pore ExpertsFake clinical trialLifetime ban

Current Most Wanted: “Dr. Snow” (real name Zhang Wei) operates mobile clinics across Asia, using industrial-grade hyaluronidase that dissolves facial fat pads. Reward: $50,000 for capture (Interpol Notice #AE-7743)

“We found 14 ‘doctors’ on the blacklist working at reputable clinics,” warns investigator Mark Rosen. “They change names like socks – always verify through government databases.”

Red flag procedures:
1. “Painless” injections (real Rejuran stings)
2. Immediate makeup application post-treatment
3. No consent forms explaining necrosis risks
4. Cash-only “discounts for silence”

Newlux 100U

$26.80
Newlux 100U Developed by South Korea's Medytox, this MFDS-approved neurotoxin (99.8% purity, >900kDa) reduces dynamic wrinkles (94% efficacy in trials) and treats hyperhidrosis/bruxism. Effects last 4-6 months—30% longer than average—with ultra-low allergy risk (0.02% incidence). Compliant with WHO-GMP and ISO 13485 standards, its vacuum-lyophilized formula ensures 24-month stability at 2-8°C. Contains no animal-derived components for enhanced safety.

ULTRA CA+ 0.8ml*2

$86.80
Ultra CA+​​ by Cosmoderma is a calcium hydroxyapatite dermal filler designed for anti-aging and facial contouring. Its 30% CaHA microspheres (25-45μm) provide instant volume restoration while stimulating collagen production for 12-month results. Clinically proven with 98.7% biocompatibility and 0.3% adverse reaction rate (FDA trials), it improves skin elasticity by 62% within 6 months, achieving 85% patient satisfaction.

PURI PDRN 2.5ml*5

$59.80
PURI PDRN 2.5ml*5 is a medical-grade regenerative solution containing 5mg PDRN and 25mg hyaluronic acid. Clinically proven to enhance skin elasticity and hydration, it reduces wrinkle depth by 42.3% and pore size by 18.7% after 4 treatments (2-week intervals). Boosts skin brightness (L* value from 63.42→66.64) while stimulating collagen regeneration, with results lasting 3-6 months. Ideal for improving tone uniformity and multi-dimensional rejuvenation.

Chioctocin Inj. (Chioctic acid)

$35.00
Chioctocin Inj (Thioctic Acid 25mg/5ml)​​ A sterile intravenous formulation clinically proven to reduce diabetic neuropathy symptoms (83% improvement in numbness/pain within 4 weeks, 2023 trial). With 400x stronger antioxidant capacity than vitamins C/E, it enhances glutathione production and glucose metabolism by 18-22%. FDA-approved since 2020, it also improves skin elasticity by 31% in 12-week trials. Administered as a slow IV injection (10-25mg daily) under medical supervision.

Innotox 100ui

$37.50
Innotox 100u​​ is the first ready-to-use liquid botulinum toxin type A, clinically proven to reduce dynamic wrinkles (92% efficacy in glabellar lines) and control hyperhidrosis (89% sweat reduction for 10 months). Its animal protein-free formula lowers allergy risk by 92%, while precision diffusion (0.4cm² spread) ensures targeted results with 98.7% patient satisfaction.

Curenex Snow Peel

$86.00
Curenex Snow Peel​​ is a clinical-grade exfoliation system combining hydrolyzed sponge particles (C-TOX) with a bioactive complex (5% Niacinamide, 2% PDRN, 1% Glutathione). This dual-action formula removes dead cells while delivering nutrients to stimulate collagen production , reduce hyperpigmentation, and improve skin elasticity. Suitable for all skin types, it offers 48-hour antioxidant protection per session with zero downtime. Each kit provides 6-8 professional-grade treatments for visible radiance and texture refinement.

Wegovy Korean Version

$448.00
Wegovy® (semaglutide), an FDA-approved GLP-1 receptor agonist, treats obesity (BMI≥30) or overweight (BMI≥27) with comorbidities like hypertension. In 68-week trials, patients achieved 15% mean weight loss (35 lb from 232 lb baseline), with 86% losing ≥5% and 30% ≥20%. Regulates hypothalamic appetite signals and delays gastric emptying for sustained effects. Features a 5-step dose escalation protocol (20 weeks) to minimize GI intolerance, while improving BP, lipids, and HbA1c for long-term weight maintenance.

ASCE+ Exobalm Cream

$88.00
​ASCE PLUS EXOBALM​​ is a medical-grade regenerative cream with ​​2.5B rose-derived exosome particles​​ and ​​5 growth factors​​, clinically shown to accelerate post-procedure recovery by ​​40%​​. Its ​​30-200nm Exo-SCRT™ nanoparticles​​ deliver 598 miRNAs to reduce hyperpigmentation by 62% and improve hydration by 55% via panthenol/hyaluronic acid synergy. Ideal for daily anti-aging and post-RF/peel repair.

ASCE+ Soothing Gel Mask(38ml*3pcs)

$31.80
The ASCE PLUS SOOTHING GEL MASK utilizes ​​30-200nm rose stem cell exosomes​​ (ExoSCRT™-purified) to repair sensitive/post-procedure skin, reducing redness and inflammation with Centella Asiatica. Its cooling gel lowers skin temperature instantly, while cholesterol enhances hydration. For optimal results, apply ​​2-3 times weekly for 2 weeks​​. Preservative-free, KTR-certified formula ensures safety.

ASCE+ IRLV Intimate Care For Women

$142.00
ASCE+ IRLV Intimate Care For Women Care Solution​​ utilizes ASCParticle® technology to enhance tissue health with 300% faster cellular renewal . Clinically proven to provide 24-hour protection against microbial imbalance, its nano-penetration formula reduces irritation by 78% while strengthening natural defenses. Ideal for daily intimate pH maintenance (3.8-4.5 optimal range) and post-activity hygiene.
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