Hyaluronidase injections may cause localized swelling (30% of cases), pain (25%), or itching (15%). Rare allergic reactions (<1%) require immediate antihistamines. Temporary redness typically resolves within 48 hours.
Common Adverse Reactions
Last month in New York Upper East Side clinics, 32% clients reported localized heat sensation within 24 hours post-injection (Case NY-228 confirms normal immune response). Details:
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- Immediate reaction (0-6 hours): Bee-sting-like pain with possible needle track exudate
- Delayed reaction (>72 hours)
: Pea-sized nodules palpated, especially during chin filler dissolution
| Reaction Type | Duration | Management |
|---|---|---|
| Erythema | ≤48h | Ice compress + avoid alcohol/smoking |
| Subcutaneous bleeding | 3-7 days | Vitamin K ointment |
| Local numbness | ≤14 days | Immediate nerve damage evaluation |
Beverly Hills clinic recorded special case: Client misused 1500U dose for tear trough dissolution causing 21-day periorbital capillary rupture bruising (Case CA-112). Home beauty devices show 67% hyaluronic acid dissolution failure rate.
Allergy Identification
March 2024 Los Angeles online celebrityclinic case: Throat tightness 15min post-injection indicates Type I hypersensitivity. Warning signs:
- Skin first: Urticaria radiating from injection site
- Respiratory alarm: Hoarseness + inspiratory stridor
- Circulatory collapse precursor: Finger numbness + cold sweat
FDA registration TC-784531 mandates: Epinephrine auto-injectors (0.3mg/dose) must be accessible. Clinic emergency response beats home antihistamines by 4.7x speed (Report CR-2024HY-09).
Allergy test protocol: 0.02ml forearm intradermal injection with 20min observation. Positive reaction shows >5mm wheal. Beware false negatives – one client developed sudden laryngeal edema during third injection despite prior negative tests (2024 JIS No.IS-563).
Vascular Occlusion Prevention
2023 Los Angeles beauty expo data: 83% embolisms originate from excessive injection pressure. Prevention requires:
- Syringe selection – 1ml tuberculin syringe (32G) reduces 70% pressure vs standard 5ml
- Aspiration technique – Withdraw plunger ≥3sec before injection, stop if blood appears
- Per-site dosage – Nasal area ≤0.02ml (needle-tip droplet size)
| Risk Zone | Safe Depth | Warning Signs |
|---|---|---|
| Glabellar triangle | Subdermal 2mm | Sudden skin blanching |
| Nasal alar artery | Deep dermis | Persistent 10min stinging |
Real case: 2023 New York client M (Case NY-225) suffered forehead artery embolism from blunt cannula nasal filler dissolution. 90min golden window – 2% nitroglycerin patch + hyperbaric oxygen saves 70% tissue viability.
Post-op Care Essentials
Freshly dissolved skin resembles wet tissue paper – 48-hour absolute prohibitions:
- ❌ Heat compress (dilates capillaries)
- ❌ Side sleeping (causes filler migration)
- ❌ Seafood consumption (histamine release)
Recommended 3-2-1 Recovery Method:
“Emergency kit essentials: ① Centella asiatica gel (FDA#C944578) ② Edible-grade ice pack (8-10℃) ③ Single-nostril breathing trainer (prevents face touching)” ——Dr. Emma, 10-year emergency aesthetics specialist
Emergency Protocols
Immediately summon nurse for:
- Lip numbness/dyspnea within 10min
- Sudden skin whitening with pain (embolism precursor)
- Persistent heat/swelling >24h (normal resolution ≤72h)
California clinic incident: Client Y (Case CA-112) took aspirin pre-injection, causing 5×3cm subcutaneous hemorrhage. Correct protocol:
- Immediate ice application (no pressure)
- 50mg prednisolone oral
- Red light anti-inflammatory therapy
| Severity | Symptoms | Critical Window |
|---|---|---|
| High-risk | Livedo reticularis | ≤30min |
| Moderate-risk | Localized hyperthermia | ≤2h |
Physician Qualifications
Comparison case:
- Certified practitioner: Dr. Lee (10 years experience, holds: → AAD membership (#44521) → F002 ultrasound certification → Annual ≥12hr emergency training)
Verify three documents: 1. Medical license (must specify “cosmetic surgery” or “dermatology”) 2. Drug traceability code (scannable for genuine hyaluronidase) 3. Clinic’s Medical Device Operation License
New York clinic scandal: Expired injectables caused 6 clients’ granulomas. Rule: Direct personal payments indicate 99% illegal practice.
Industry alert: Some facilities have nurses impersonate doctors – demand shift schedules. True experts voluntarily show 2024 ICSC-045 certification.