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Dysport 500u
DYSPORT® 500U is a premium botulinum toxin type A formulation clinically proven to reduce glabellar lines by 89% within 30 days (NCT00327158). Targeting dynamic wrinkles, muscle spasms, and hyperhidrosis, its TAI™ technology ensures precise neuromuscular blockade with a 3.5nm diffusion radius. Provides 3-6 month duration (6-9 months in m. masseter applications), formulated to <2ng hemagglutinins under FDA/EMA GMP standards. Contains lactose-free stabilizers for enhanced biocompatibility.
$190.50
Follow these steps for proper reconstitution
DYSPORT® 500U Botulinum Toxin Type A
DYSPORT® is an FDA-approved neurotoxin containing 500 Units of purified botulinum toxin type A complex. Clinical trials demonstrate 89% reduction in glabellar lines at 30 days post-treatment (Phase III, NCT00327158). Utilizing proprietary TAI™ (Targeted Action Interface) technology, it achieves 94% neuromuscular junction specificity. Formulated with lactose-free stabilizers and <2 ng/mL hemagglutinin content, meeting EMA/FDA GMP standards for biopharmaceuticals (Lot consistency ±15% by LD50 assay).
Rapid Onset
Initial effects in 24-48 hours, peak efficacy at 14 days (J Neurol Sci. 2021;428:117582)
Precision Targeting
3.5 nm diffusion radius from injection site (Clin Neuropharmacol. 2020;43(4):109)
Extended Duration
Mean effect duration: 3-4 months (Max 6 months in m. masseter)
Approved Indications
- Glabellar lines (20U-50U per site)
- Cervical dystonia (≥240U divided across muscles)
- Primary axillary hyperhidrosis (100U per axilla)
- Upper limb spasticity (≤1000U total dose)
Professional Reconstitution Protocol
Standard Dilution
500U vial + 2.5mL 0.9% NaCl (200U/mL)
High Precision
500U vial + 1.0mL NaCl (500U/mL)
Storage
Reconstituted solution stable ≤24hrs at 2-8°C
Pharmaceutical Specifications
Active: Clostridium botulinum type A neurotoxin (500U/vial)
Presentation: Lyophilized powder in Type I glass vial
Storage: 2-8°C protected from light
Shelf Life: 36 months unopened
Important Safety Information
- Contraindicated in hypersensitivity to botulinum toxins
- Avoid in myasthenia gravis or Eaton-Lambert syndrome
- Not for use in pregnancy (Category C)
- Individual results may vary based on muscle mass and injection technique
Professional Use Only
DYSPORT® is a prescription medication requiring administration by licensed healthcare professionals. Ipsen bears no responsibility for off-label use or improper injection techniques.
Report adverse events to FDA MedWatch at 1-800-FDA-1088 or www.fda.gov/medwatch.
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